What Is NB.1.8.1?
COVID-19 variant NB.1.8.1 was first detected in China in January 2025 and has since spread rapidly across the U.S. According to CDC estimates, it currently makes up as much as 37% of all COVID-19 cases in the United States as of early June, after being almost nonexistent before March.
According to virologists, NB.1.8.1 is a mutation of the LP.8.1 variation and seems to spread more quickly and elude immune defenses more effectively than earlier iterations.
Is It Risky? The CDC and WHO Weigh In
The global risk of NB.1.8.1 is now rated as low by the World Health Organization (WHO). However, because of the variant’s potential for enhanced spread, it suggests more observation.
The Moderna booster and other 2024–2025 COVID-19 vaccines are still expected to be beneficial in preventing the severe outcomes that this variant can cause, according to the CDC.
NB.1.8.1 Common Symptoms
The CDC has not identified any distinct symptoms that are exclusive to NB.1.8.1. Early accounts and anecdotal evidence, however, associate it with a severe painful throat that many who experience it refer to as the “razor blade throat.”
Typical COVID-19 symptoms are still present:
- A sore throat
- Chills or fever
- Coughing
- Runny nose or congestion
- Breathlessness
- Fatigue and pains in the muscles
- headache and nausea
- Loss of flavor or aroma
When to Seek Medical Help
Per CDC guidance, seek immediate medical attention if you experience:
- Trouble breathing
- Chest pain or pressure
- Confusion
- Inability to stay awake
- Blue or gray skin, lips, or nails
Who Should Get Vaccinated Now?
As of January 2025, the CDC recommends the updated COVID-19 vaccine for:
- Everyone 65 and older
- Those with underlying health conditions
- Residents of long-term care facilities
- People at risk of long COVID
However, Health Secretary Robert F. Kennedy Jr. has removed COVID vaccines from the routine schedule for healthy children and pregnant women, making it harder for some to access vaccines or receive insurance coverage.
How to Get Tested for Free
Free COVID-19 tests are still available under the ICATT federal program for uninsured individuals.
Visit testinglocator.cdc.gov/Search to find a free testing site near you.
Is This a Warning for What’s Ahead?
With NB.1.8.1 now nearly tied with the leading Omicron variant LP.8.1, and other strains like XFG and XFC circulating, experts emphasize continued vigilance, vaccination, and early detection through testing.
Source: USA Today
